Haemodynamic definitions and updated clinical classification of pulmonary hypertension
Review Article | By Simonneau G, Montani D, Celermajer DS et al.
Pulmonary hypertension due to left heart disease
Review Article | By Vachiéry JL, Tedford RJ, Rosenkranz S et al.
Aortic Valve Stenosis Treatment Disparities in the Underserved JACC Council Perspectives
Perspective | By W Batchelor, S Anwaruddin, L Ross et al.
Underserved minorities make up a disproportionately small subset of patients in the United States undergoing transcatheter and surgical aortic valve replacement for aortic stenosis. The reasons for these treatment gaps include differences in disease prevalence and patient, health care system, and disease-related factors. This has major implications not only for minority patients, but also for other groups who face similar challenges in accessing...
Review Article | By Suchard MA, Schuemie MJ, Krumholz HM et al.
BACKGROUND - Uncertainty remains about the optimal monotherapy for hypertension, with current guidelines recommending any primary agent among the first-line drug classes thiazide or thiazide-like diuretics, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, dihydropyridine calcium channel blockers, and non-dihydropyridine calcium channel blockers, in the absence of comorbid indications. Ra...
Consensus | By Pieske B Tschöpe C, de Boer RA et al.
Making a firm diagnosis of chronic heartfailure with preservedejectionfraction (HFpEF) remains a challenge. We recommend a new stepwise diagnostic process, the 'HFA-PEFFdiagnosticalgorithm'. Step 1 (P=Pre-test assessment) is typically performed in the ambulatory setting and includes assessment for HF symptoms and signs, typical clinical demographics (obesity, hypertension, diabetes mellitus, elderly, atrial fibrilla...
Original Research | By Serruys PW, Morice MC, SYNTAX Investigators.
BACKGROUND - Percutaneous coronary intervention (PCI) involving drug-eluting stents is increasingly used to treat complex coronary artery disease, although coronary-artery bypass grafting (CABG) has been the treatment of choice historically. Our trial compared PCI and CABG for treating patients with previously untreated three-vessel or left main coronary artery disease (or both). METHODS - We randoml...
Expansion or contraction of stenting in coronary artery disease?
Editorial | By Taggart DP, Pagano D.
In the past four decades, more than 20 trials of percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG) have tested whether iterative technical advances in PCI have made it as effective as CABG in patients with stable coronary artery disease. The clinical relevance of most of these trials to real-world practice has, however, been plagued by three issues. F...
A Novel Algorithm for Treating Chronic Total Coronary Artery Occlusion
Original Research | By H Tanaka, E Tsuchikane, T Muramatsu et al.
BACKGROUND - Guidewire manipulation time is rarely used in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) strategies. OBJECTIVES - This study sought to develop an algorithm based on angiographic characteristics and guidewire manipulation time. METHODS - This study assessed 5,843 patients undergoing CTO PCI between January 2014 and December 2017 and enr...