Clinical Trial | By FM Asch, PA Grayburn, the COAPT Investigators.
BACKGROUND- In the COAPT trial among patients with heart failure (HF) and moderate-to-severe (3+) or severe (4+) secondary mitral regurgitation (SMR), patients treated with the transcatheter mitral valve replacement (TMVR) had reduced rates of HF hospitalization and mortality compared with guideline-directed medical therapy (GDMT) alone. OBJECTIVES- To describe the echocardiographic patient q...
Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation: Outcomes at 2 years
Clinical Trial | By Iung B, Armoiry X, MITRA-FR Investigators.
Clinical Trial | By X Chen, XB Li, the DKCRUSH-V Investigators.
Clinical Trial | By SJ Baron, EA Magnuson, the PARTNER 3 Investigators.
BACKGROUND - In patients with severe aortic stenosis (AS) at low surgical risk, treatment with transcatheter aortic valve replacement (TAVR) results in lower rates of death, stroke, and re-hospitalization at 1 year compared with surgical aortic valve replacement; however, the effect of treatment strategy on health status is unknown. OBJECTIVES - This study sought to compare health status outcomes of TAVR...
Informed Shared Decisions for Patients with Aortic Stenosis
Valve replacement is the only effective treatment for adults with severe, symptomatic aortic stenosis. The ideal prosthetic valve would be associated with minimal risk and discomfort at implantation, would have hemodynamics similar to those of a normal valve, would not require anticoagulation, and would be durable for the patient’s lifetime. We are moving closer to this goal, as evidenced by sequential randomized clinica...
Clinical Trial | By SJ Hong, GS Mintz, the IVUS-XPL Investigators.
OBJECTIVES - The goal of this study was to evaluate whether the beneficial effect of use of intravascular ultrasound (IVUS) is sustained for long-term follow-up. BACKGROUND - The use of IVUS promoted favorable 1-year clinical outcome in the IVUS-XPL trial. It is not known, however, whether this effect is sustained for long-term follow-up. METHODS - The IVUS-XPL trial ...
Original Research | By JJ Zhang, XF Gao, the ULTIMATE Investigators.
Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease
Clinical Trial | By Stone GW, Kappetein AP, EXCEL Trial Investigators.
BACKGROUND - Long-term outcomes after percutaneous coronary intervention (PCI) with contemporary drug-eluting stents, as compared with coronary-artery bypass grafting (CABG), in patients with left main coronary artery disease are not clearly established. METHODS - We randomly assigned 1905 patients with left main coronary artery disease of low or intermediate anatomical complexity (according to...
Original Research | By B Iung , V Delgado ,the EORP VHD II Investigators.