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荐读文献
Management of Acute Myocardial Infarction During the COVID-19 Pandemic
CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
SCAI Expert Consensus Statement Update on Best Practices for Transradial Angiography and Intervention
Original Research | By JA Doll , RS Hira , KE Kearney et al.
Complications of percutaneous coronary intervention (PCI) may have significant impact on patient survival and healthcare costs. PCI procedural complexity and patient risk are increasing, and operators must be prepared to recognize and treat complications, such as perforations, dissections, hemodynamic collapse, no-reflow, and entrapped equipment. Unfortunately, few resources exist to train operators in PCI complication management. Uncerta...
Chimney technique in a TAVR-in-TAVR procedure with high risk of left main artery ostium occlusion
Clinical Case Study | By A Dibie, Q Landolff, A Veugeois et al.
An 87-year-old woman was referred to our centre for a valve-in-valve transcatheter aortic valve replacement (TAVR). She underwent a TAVR procedure with implantation of a SAPIEN XT 26 mm (Edwards Lifesciences) bioprosthesis 7 years before but subsequently developed symptomatic aortic valve failure (mean gradient = 64 mmHg). Pre-procedural computed tomography (CT) scan identified a low height between the valvular...
Effect of Evolocumab on Complex Coronary Disease Requiring Revascularization
Clinical Trial | By K Oyama, RHM Furtado, BA Bergmark et al.
BACKGROUND - Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors induce plaque regression and reduce the risk of coronary revascularization overall. OBJECTIVES - To evaluate the ability of PCSK9 inhibitors to reduce the risk of complex coronary atherosclerosis requiring revascularization. METHODS - FOURIER was a randomized trial of the PCSK9 inhibitor evolocum...
Clinical Trial | By J Silvain, B Lattuca, ALPHEUS investigators et al.
Original Research | By M Fedchenko, Z Mandalenakis, KW Giang et al.
Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy
Clinical Trial | By P Thavendiranathan, T Negishi, SUCCOUR investigators et al.
BACKGROUND - In patients at risk of cancer therapy-related cardiac dysfunction (CTRCD), initiation of cardio-protective therapy (CPT) is constrained by the low sensitivity of EF for minor changes in LV function. Global longitudinal strain (GLS) is a robust and sensitive marker of LV dysfunction, but existing observational data have been insufficient to support a routine GLS-guided strategy for CPT. OBJECTIV...
Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction
Clinical Trial | By TJ Ford, D Corcoran, S Padmanabhan et al.
Review Article | By F Moroni, E Ammirati, AH Hainsworth et al.
Cardiac and cerebrovascular diseases are currently the leading causes of mortality and disability worldwide. Both the heart and brain display similar vascular anatomy, with large conduit arteries running on the surface of the organ providing tissue perfusion through an intricate network of penetrating small vessels. Both organs rely on fine tuning of local blood flow to match metabolic demand. Blood flow regulation requires adequate functioning...
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