Original Research | By G Casu, G D'Angelo, P Merella et al.
BACKGROUND - Intracranial hemorrhage (ICH) represents the most serious complication of oral anticoagulant therapy (OAT) in patients with atrial fibrillation (AF), and AF patients with previous ICH are a challenge for clinicians. Left atrial appendage (LAA) occlusion has emerged as an alternative option for AF patients not suitable for OAT. Currently, few data are available on long term outcomes after LAA occlusion in this populati...
The Prognostic Value of Exercise Echocardiography After Percutaneous Coronary Intervention
Original Research | By A Marques, I Cruz, I João et al.
BACKGROUND - Exercise echocardiography (EE) is a valuable noninvasive method for diagnostic and prognostic assessment of ischemic cardiac disease. The prognostic value of a negative EE test is well known overall, but its role in patients who undergo percutaneous coronary intervention remains poorly validated. The aim of this study was to ascertain the prognostic value of treadmill EE and to determine predictors of cardiac events in this ...
Clinical Trial | By B Cortese, GD Palma, MG Guimaraes et al.
OBJECTIVES - This study sought to compare the performance of a novel drug-coated balloon (DCB) (Elutax SV, Aachen Resonance, Germany), with an everolimus-eluting stent (EES) (Abbott Vascular, Santa Clara, California) in patients with de novo lesions. BACKGROUND - Small vessel coronary artery disease (SVD) represents one of the most attractive fields of application for DCB. To date, several devices have bee...
Original Research | By S Yang, B-K Koo, M Hoshino et al.
OBJECTIVES - The goal of this study was to investigate the association of stenosis and plaque features with myocardial ischemia and their prognostic implications. BACKGROUND - Various anatomic, functional, and morphological attributes of coronary artery disease (CAD) have been independently explored to define ischemia and prognosis. METHODS - A total of 1,013 ves...
Original Research | By H Rahman, CM Scannell, A Chiribiri et al.
Clinical Trial | By Y Onuma, N Kogame, OPTIMUM Investigators et al.
Original Research | By BJ Forrestal, BC Case, C Yerasi et al.
BACKGROUND - The supra-annular leaflet position and tall stent frame of the self-expanding Evolut PRO or Evolut PRO+ transcatheter heart valves (THVs) may cause coronary occlusion during transcatheter aortic valve replacement (TAVR)-in-TAVR and present challenges for future coronary access. We sought to evaluate the risk of TAVR-in-TAVR with Evolut PRO or Evolut PRO+ THVs and the feasibility of future cor...
Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure
Original Research | By ESJ Tan, S-P Chan, O-W Liew et al.
BACKGROUND - Consideration of circulating biomarkers for risk stratification in heart failure (HF) is recommended, but the influence of atrial fibrillation (AF) on prognostic performance of many markers is unclear. We investigated the influence of AF on the prognostic performance of circulating biomarkers in HF. METHODS - N-terminal pro-B-type natriuretic peptide (NT-proBNP), mid-regional-pro-atrial natr...