Clinical Trial | By K Kanenawa, K Yamaji, H Tashiro et al.
BACKGROUND - We sought to evaluate the impact of patient selection for the STOPDAPT-2 trial (Short and Optimal Duration of Dual Antiplatelet Therapy After Everolimus-Eluting Cobalt-Chromium Stent-2) on clinical outcomes in a registry from a single center that participated in the STOPDAPT-2 trial. METHODS - Among 2190 consecutive patients who underwent percutaneous coronary intervention usin...
Clinical Trial | By G Ducrocq, JR Gonzalez-Juanatey, E Puymirat et al.
IMPORTANCE - The optimal transfusion strategy in patients with acute myocardial infarction and anemia is unclear. OBJECTIVE - To determine whether a restrictive transfusion strategy would be clinically noninferior to a liberal strategy. DESIGN, SETTING, AND PARTICIPANTS - Open-label, noninferiority, randomized trial conducted in 35 hospitals in France and Spain...
Invasive Coronary Physiology After Stent Implantation: Another Step Toward Precision Medicine
Review Article | By S Biscaglia , B Uretsky , E Barbato , C Collet et al.
Intracoronary physiology is routinely used in setting the indication for percutaneous coronary intervention (PCI) but seldom in assessing procedural results. This attitude is increasingly challenged by accumulated evidence demonstrating the value of post-PCI functional assessment in predicting long-term patient outcomes. Besides fractional flow reserve, a number of new indexes recently incorporated to clinical practice, including nonhyperemic pr...
From organic and inorganic phosphates to valvular and vascular calcifications
MINOCA: a heterogenous group of conditions associated with myocardial damage
Review Article | By T Singh, AR Chapman, NL Mills et al.
Myocardial infarction with non-obstructive coronary arteries (MINOCA) was first described over 80 years ago. The term has been widely and inconsistently used in clinical practice, influencing various aspects of disease classification, investigation and management. MINOCA encompasses a heterogenous group of conditions that include both atherosclerotic and non-atherosclerotic disease resulting in myocardial damage that is not due to obstructive coronary ...
Letter | By M Elharram, E Hillier, S Hawkins et al.
Please click on the "Article Link" to get access to the original paper link!
Clinical Trial | By TA Zelniker, M Ardissino, F Andreotti et al.
Clinical Trial | By AM Maznyczka, PJ McCartney, KG Oldroyd et al.
BACKGROUND - The index of microcirculatory resistance (IMR) of the infarct-related artery and left ventricular end-diastolic pressure (LVEDP) are acute, prognostic biomarkers in patients undergoing primary percutaneous coronary intervention. The clinical significance of IMR and LVEDP in combination is unknown. METHODS - IMR and LVEDP were prospectively measured in a prespeci...
Original Research | By HR Reynolds, A Maehara, RY Kwong et al.
Original Research | By R Modolo, M van Mourik, PW Serruys et al.
BACKGROUND - Quantitative assessment of regurgitation after TAVR through aortography using videodensitometry is simple, reproducible, and validated in vitro, in vivo, in clinical trials, and in “real-world” patients. However, thus far the assessment has been done offline. METHODS - This was a single center, prospective, proof-of-principle, feasibility study. One hundred consecutive patients with aortic stenosis a...