Original Research | By K Dziopa, FW Asselbergs, J Gratton et al.
Criteria for Iron Deficiency in Patients With Heart Failure
Original Research | By G Masini , FJ Graham, P Pellicori et al.
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Guideline | By TA McDonagh, M Metra, ESC Scientific Document Group
Original Research | By D Han, A Lin, K Kuronuma et al.
IMPORTANCE - Distinct plaque locations and vessel geometric features predispose to altered coronary flow hemodynamics. The association between these lesion-level characteristics assessed by coronary computed tomographic angiography (CCTA) and risk of future acute coronary syndrome (ACS) is unknown. OBJECTIVE - To examine whether CCTA-derived adverse geometric characteristics (AGCs) of coronary lesi...
Clinical Trial | By C Laudani, A Greco,G Occhipinti et al.
OBJECTIVES - The aim of this study was to compare short dual antiplatelet therapy (DAPT) and de-escalation in a network meta-analysis using standard DAPT as common comparator. BACKGROUND - In patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI), shortening DAPT and de-escalating to a lower potency regimen mitigate bleeding risk. These strategies have never been ran...
A Score to Assess Mortality After Percutaneous Mitral Valve Repair
Original Research | By S Raposeiras-Roubin , M Adamo , X Freixa et al.
BACKGROUND - Risk stratification for transcatheter edge-to-edge mitral valve repair (TEER) is paramount in the decision-making process for treating severe mitral regurgitation (MR). OBJECTIVES - This study sought to create and validate a user-friendly score (MitraScore) to predict the risk of mortality in patients undergoing TEER. METHODS - The derivation cohort was based on a m...
Predictors of Left Main Coronary Artery Disease in the ISCHEMIA Trial
Original Research | By R Senior , HR Reynolds , JK Min et al.
BACKGROUND - Detection of ≥50% diameter stenosis left main coronary artery disease (LMD) has prognostic and therapeutic implications. Noninvasive stress imaging or an exercise tolerance test (ETT) are the most common methods to detect obstructive coronary artery disease, though stress test markers of LMD remain ill-defined. OBJECTIVES - The authors sought to identify markers of LMD as detected o...
Original Research | By LC Schröder, A Holkeri, A Eranti et al.
Original Research | By A Mehta, N Vasquez, CR Ayers et al.
BACKGROUND - Elevated lipoprotein(a) [Lp(a)] and coronary artery calcium (CAC) score are individually associated with increased atherosclerotic cardiovascular disease (ASCVD) risk but have not been studied in combination. OBJECTIVES - This study sought to investigate the independent and joint association of Lp(a) and CAC with ASCVD risk. METHODS - Plasma Lp(a) and...