Prognostic implication of lipidomics in patients with coronary total occlusion undergoing PCI
Original Research | By Y Zhou, XD Wang, JY Qian et al.
BACKGROUND - Predictors of prognosis in patients with coronary chronic total occlusion (CTO) undergoing elective percutaneous coronary intervention (PCI) have remained lacking. Lipidomic profiling enable researchers to associated lipid species with disease progression and may improve the prediction of cardiovascular events. METHODS - In the present study, 781 lipids were measured by targeted lipidom...
Original Research | By J Kan, SL Chen, DEFINITION II Investigators et al.
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
Guideline | By ESC/ERS Scientific Document Groupnt of pulmonary hypertension
Aggressive lipid-lowering therapy after percutaneous coronary intervention – for whom and how?
Original Research | By PM Ridker, DL Bhatt, AD Pradhan et al.
BACKGROUND - Inflammation and hyperlipidaemia jointly contribute to atherothrombotic disease. However, when people are treated with intensive statin therapy, the relative contributions of inflammation and hyperlipidaemia to the risk of future cardiovascular events might change, which has implications for the choice of adjunctive cardiovascular therapeutics. We aimed to evaluate the relative importance of high-sensitivity C-react...
Original Research | By J Zhang, J Kan, S-L Chen et al.
BACKGROUND — The differential treatment effect of pulmonary artery denervation (PADN) in pulmonary arterial hypertension (PAH) patients with different risk burdens remains unclear. This study aimed to determine the effectiveness of PADN in low vs. intermediate-high-risk PAH patients. METHODS — In total, 128 patients with treatment naive PAH included in the PADN-CFDA t...