Original Research | By M Alkhouli, CA Du , A Killu et al.
BACKGROUND - Data on the impact of residual peri-device leak after left atrial appendage occlusion (LAAO) are limited. OBJECTIVES - The goal of this study was to explore the association of peri-device leak with adverse clinical events. METHODS - The National Cardiovascular Data Registry LAAO Registry was queried to identify patients undergoing LAAO between January...
Original Research | By EJ Hollenberg, F Lin, MJ Blaha et al.
OBJECTIVES - Among patients with low to high coronary artery calcium (CAC) scores, our aims were to quantify co-occurring obstructive and nonobstructive noncalcified plaque and serial progression of atherosclerotic plaque volume. BACKGROUND - Among symptomatic patients, it remains unclear whether a CAC score alone is sufficient or misses a sizeable burden and progressive risk associated with obstructi...
Percutaneous Pulmonary Angioplasty for Patients With Takayasu Arteritis and Pulmonary Hypertension
Original Research | By Y-P Zhou , Y-P Wei , Y-J Yang et al.
BACKGROUND - Percutaneous transluminal pulmonary angioplasty (PTPA) is a treatment modality for chronic thromboembolic pulmonary hypertension, but whether it can be applied to Takayasu arteritis–associated pulmonary hypertension (TA-PH), another chronic obstructive pulmonary vascular disease, remains unclear. OBJECTIVES - This study sought to investigate the efficacy and safety of PTPA for TA-P...
Optical Coherence Tomography to Assess Proximal Side Optimization Technique in Crush Stenting
Mathematical modelling of endovascular drug delivery: balloons versus stents
Clinical Trial | By J Delgado-Lista, J Lopez-Miranda, CORDIOPREV Investigators et al.
BACKGROUND - Mediterranean and low-fat diets are effective in the primary prevention of cardiovascular disease. We did a long-term randomised trial to compare the effects of these two diets in secondary prevention of cardiovascular disease. METHODS - The CORDIOPREV study was a single-centre, randomised clinical trial done at the Reina Sofia University Hospital in Córdoba, Spain. Patients wit...
Circadian Cadence and NR1D1 Tune Cardiovascular Disease
Original Research | By YC Zhao , XY Lu , F W et al.
BACKGROUND - Shift work is associated with increased risk of acute myocardial infarction (AMI) and worsened prognosis. However, the mechanisms linking shift work and worsened prognosis in AMI remain unclear. OBJECTIVES - This study sought to investigate the impact of shift work on reperfusion injury, a major determinant of clinical outcomes in AMI. METHODS - Study p...
Review Article | By DJ van Ginkel, WL Bor, E Fabris et al.
Thromboembolic and bleeding complications negatively impact recovery and survival after transcatheter aortic valve implantation (TAVI). Particularly, there is a considerable risk of ischaemic stroke and vascular access related bleeding, as well as spontaneous gastro-intestinal bleeding. Therefore, benefit and harm of antithrombotic therapy should be carefully balanced. This review summarizes current evidence on peri- and post-procedural antit...
Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium
Original Research | By S Gencer, Y Döring, EPC van der Vorst et al.