Consensus from the 5th European Bifurcation Club meeting
Clinical Trial | By Chen SL, Ye F, Stone GW et al.
OBJECTIVES - This study sought to compare the outcomes of fractional flow reserve (FFR)-guided and angiography (Angio)-guided provisional side-branch (SB) stenting for true coronary bifurcation lesions. BACKGROUND - Angio-guided provisional SB stenting after stenting of the main vessel provides favorable outcomes for the majority of coronary bifurcation lesions. Whether an FFR-guided provisional stenting app...
Original Research | By Shiono Y1 Kubo T, Tanaka A et al.
OBJECTIVES - The aim of this study was to investigate the impact of myocardial area supplied by the coronary artery on fractional flow reserve (FFR). BACKGROUND - Various factors other than the degree of epicardial stenosis influence the physiological significance of a coronary artery stenosis. METHODS - A total of 296 coronary lesions in 217 patients were analyzed by quantitative coronary...
Clinical Trial | By Chen SL, Ye F, Zhang JJ et al.
BACKGROUND - The effects of intravascular ultrasound (IVUS)-guided complex approaches using drug-eluting stents (DES) for coronary bifurcation lesions on clinical outcomes has not yet been studied in detail. OBJECTIVE - Our objective was to analyze the difference in 1-year outcomes following two-stent techniques involving implantation of DES for coronary bifurcation lesions between IVUS-guided and ...
Clinical Trial | By Chen SL, Sheiban I, Xu B et al.
OBJECTIVES - The present study established criteria to differentiate simple from complex bifurcation lesions and compared 1-year outcomes stratified by lesion complexity after provisional stenting (PS) and 2-stent techniques using drug-eluting stents. BACKGROUND - Currently, no criterion can distinguish between simple and complex coronary bifurcation lesions. Comparisons of PS and 2-stent strategies strati...
Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients
Original Research | By ML Henry, JG Niu, N Zhang et al.
OBJECTIVES - This study sought to determine the rate of chemotherapy-related cardiotoxicity and to estimate adherence to recommendations for cardiac monitoring among breast cancer patients treated with chemotherapy. BACKGROUD - Heart failure (HF) is a known complication associated with cancer therapies. Little is known regarding the rate of chemotherapy-related cardiotoxicity and adherence to recommendati...
Stress Echocardiography and PH: What Do the Findings Mean?
Expert Opinion | By Monique A. Freund, MBBS, FACC
DEFINITIONS - There are five subtypes of pulmonary hypertension (PH) in the most recent classification from the 5th World Symposium on Pulmonary Hypertension in 2013.1 Group 1 is typical pulmonary arterial hypertension (PAH), and group 2 is PH due to left heart disease. Group 2 PH is the most common subtype encountered in clinical practice, including in the stress echocardiography laboratory. Pre-capillary PH is invasively defined as...
Original Research | By Jinnouchi H, Kuramitsu S, Shinozaki T et al.
BACKGROUND - Percutaneous coronary intervention for heavily calcified lesions requires rotational atherectomy (RA). Long-term clinical outcomes after drug-eluting stent (DES) implantation following (RA) for heavily calcified lesions remain unclear. We assessed 5-year clinical outcomes after DES implantation following RA. METHODS AND RESULTS- Between March 2006 and September 2011, 219 consec...
Astro-CHARM, the First 10-year ASCVD Risk Estimator Incorporating Coronary Calcium
Expert Opinion | By Anum Minhas, MD; Roger S. Blumenthal, MD, FACC; Seth Shay Martin, MD, MHS, FACC
Approaches to cardiovascular disease risk assessment range in focus from the broad endpoint of global composite cardiovascular disease, including myocardial infarction (MI), stroke, coronary or peripheral revascularization, incident heart failure and atrial fibrillation, to more narrow approaches focused only on coronary events or cardiovascular mortality or to approaches in the middle looking at hard atherosclerotic cardiovascular disease (ASCVD) events such ...