Original Research | By Shavadia JS, Holmes DN, Thomas L et al.
Original Research | By Pang PS, Fermann GJ, Hunter BR et al.
Original Research | By Dreyer RP, Tavella R, Curtis JP et al.
AIMS - The prognosis of patients with MINOCA (myocardial infarction with non-obstructive coronary arteries) is poorly understood. We examined major adverse cardiac events (MACE) defined as all-cause mortality, re-hospitalization for acute myocardial infarction (AMI), heart failure (HF), or stroke 12-months post-AMI in patients with MINOCA versus AMI patients with obstructive coronary artery disease (MICAD). &nb...
Myocardial Infarction Risk Stratification With a Single Measurement of High-Sensitivity Troponin I
Original Research | By Y Sandoval, R Nowak, CR deFilippi et al.
BACKGROUND- Limited data exist on rapid risk-stratification strategies using the U.S. Food and Drug Administration–cleared high-sensitivity cardiac troponin I (hs-cTnI) assays. OBJECTIVES- This study sought to examine single measurement hs-cTnI to identify patients at low and high risk for acute myocardial infarction (MI). METHODS- This was a prospective, multicenter, observa...
Editorial | By PV Caposino, MV Kondratovich.
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Association of Silent Myocardial Infarction and Sudden Cardiac Death
Original Research | By Vähätalo JH, Huikuri HV, Holmström LTA et al.
IMPORTANCE - Myocardial infarction in the absence of major or unrecognized symptoms are characterized as silent (SMI). The prevalence of SMI among individuals who experience sudden cardiac death (SCD), with or without concomitant electrocardiographic (ECG) changes, has not previously been described in detail from large studies to our knowledge. OBJECTIVE - To determine the prevalence of SMI in individu...
Clinical Case Study | By Tsuchiya H, Nakano A, Nakamura N et al.
Coronary plaque rupture is a culprit lesion morphology of thrombotic events leading to acute coronary syndrome (ACS). Meanwhile, coronary plaque rupture often occurs silently and heals spontaneously. This phenomenon is recognized as healed plaque rupture (HPR) in pathological studies. HPR is considered to be a cause of lesion progression, although most reports have been based on ex vivo autopsy specimens, therefore HPR remains underapprecia...
Review Article | By P Sardar, JD Abbott, A Kundu et al.
Access to big data analyzed by supercomputers using advanced mathematical algorithms (i.e., deep machine learning) has allowed for enhancement of cognitive output (i.e., visual imaging interpretation) to previously unseen levels and promises to fundamentally change the practice of medicine. This field, known as “artificial intelligence” (AI), is making significant progress in areas such as automated clinical decision making, ...
Original Research | By Azzalini L, Vilca LM, Lombardo F et al.
BACKGROUND - There is controversy as to whether iso-osmolar contrast media (IOCM) are associated with lower risk of contrast-induced acute kidney injury (CI-AKI), compared with low-osmolar contrast media (LOCM). We aimed to evaluate if a differential risk of CI-AKI exists after percutaneous coronary intervention (PCI) according to different contrast media (CM) types. METHODS - We perf...