Original Research | By Y Otaki, J Betancur, T Sharir et al.
OBJECTIVES- This study compared the ability of automated myocardial perfusion imaging analysis to predict major adverse cardiac events (MACE) to that of visual analysis. BACKGROUND- Quantitative analysis has not been compared with clinical visual analysis in prognostic studies. METHODS- A total of 19,495 patients from the multicenter REFINE SPECT (REgistry of Fast Myocardial ...
Original Research | By G Pontone, D Andreini, AI Guaricci et al.
OBJECTIVES - This study aimed to evaluate the correlation between different haptoglobin (Hp) phenotypes and myocardial infarction characteristics as detected by cardiac magnetic resonance (CMR) in consecutive patients after ST-segment elevation myocardial infarction (STEMI). BACKGROUND - Hp is a plasma protein that prevents iron-mediated oxidative tissue damage. CMR has emerged as the gold standard ...
Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes
Original Research | By JM Lee, GC, B-K Koo et al.
OBJECTIVES - The authors investigated the utility of noninvasive hemodynamic assessment in the identification of high-risk plaques that caused subsequent acute coronary syndrome (ACS). BACKGROUND - ACS is a critical event that impacts the prognosis of patients with coronary artery disease. However, the role of hemodynamic factors in the development of ACS is not well-known. MET...
Primary Prevention of Sudden Cardiac Death
Guideline | By A D. Beaser; Adam S. Cifu, MD; Hemal M. Nayak.
Ventricular arrhythmias range from benign premature ventricular contractions to ventricular fibrillation and can be asymptomatic or have sudden cardiac death as the first manifestation. Sudden cardiac death is a major public health problem, accounting for 50% of all cardiovascular death.1 Although a plurality of sudden cardiac death occurs in the general population with no apparent cardiac risk factors, the risk is greatest in patients with LVE...
Original Research | By D Sibbing, D Aradi, D Alexopoulos et al.
Dual-antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the standard treatment for patients undergoing percutaneous coronary intervention. The availability of different P2Y12 receptor inhibitors (clopidogrel, prasugrel, ticagrelor) with varying levels of potency has enabled physicians to contemplate individualized treatment regimens, which may include escalation or deescalation of P2Y12-inhibiting therapy....
Original Research | By Ferencik M, Mayrhofer T, Bittner DO et al.