Editorial | By PV Caposino, MV Kondratovich.
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Association of Silent Myocardial Infarction and Sudden Cardiac Death
Original Research | By Vähätalo JH, Huikuri HV, Holmström LTA et al.
IMPORTANCE - Myocardial infarction in the absence of major or unrecognized symptoms are characterized as silent (SMI). The prevalence of SMI among individuals who experience sudden cardiac death (SCD), with or without concomitant electrocardiographic (ECG) changes, has not previously been described in detail from large studies to our knowledge. OBJECTIVE - To determine the prevalence of SMI in individu...
Effect of Systolic and Diastolic Blood Pressure on Cardiovascular Outcomes
Original Research | By AC Flint, C Conell, DL Bhatt et al.
BACKGROUND - The relationship between outpatient systolic and diastolic blood pressure and cardiovascular outcomes remains unclear and has been complicated by recently revised guidelines with two different thresholds (≥140/90 mm Hg and ≥130/80 mm Hg) for treating hypertension. METHODS - Using data from 1.3 million adults in a general outpatient population, we performed a multivariable Cox survival analysis to determine...
Clinical Case Study | By Tsuchiya H, Nakano A, Nakamura N et al.
Coronary plaque rupture is a culprit lesion morphology of thrombotic events leading to acute coronary syndrome (ACS). Meanwhile, coronary plaque rupture often occurs silently and heals spontaneously. This phenomenon is recognized as healed plaque rupture (HPR) in pathological studies. HPR is considered to be a cause of lesion progression, although most reports have been based on ex vivo autopsy specimens, therefore HPR remains underapprecia...
Review Article | By P Sardar, JD Abbott, A Kundu et al.
Access to big data analyzed by supercomputers using advanced mathematical algorithms (i.e., deep machine learning) has allowed for enhancement of cognitive output (i.e., visual imaging interpretation) to previously unseen levels and promises to fundamentally change the practice of medicine. This field, known as “artificial intelligence” (AI), is making significant progress in areas such as automated clinical decision making, ...
Original Research | By Azzalini L, Vilca LM, Lombardo F et al.
BACKGROUND - There is controversy as to whether iso-osmolar contrast media (IOCM) are associated with lower risk of contrast-induced acute kidney injury (CI-AKI), compared with low-osmolar contrast media (LOCM). We aimed to evaluate if a differential risk of CI-AKI exists after percutaneous coronary intervention (PCI) according to different contrast media (CM) types. METHODS - We perf...
Phenomapping for Novel Classification of Heart Failure With Preserved Ejection Fraction
Machine Learning Approaches in Cardiovascular Imaging
Original Research | By Henglin M, Stein G, Hushcha PV et al.
Original Research | By Fairbairn TA, Nieman K, Akasaka T et al.