Coronary Plaque Features on CTA Can Identify Patients at Increased Risk of Cardiovascular Events
Original Research | By D Andreini, M Magnoni, the CAPIRE Investigators et al.
OBJECTIVES - This study sought to assess whether coronary atherosclerosis analysis by coronary computed tomography angiography (CTA) may improve prognostic stratification among patients with diffuse coronary artery disease (CAD) BACKGROUND - Coronary CTA has recently emerged as a promising noninvasive tool for advanced analysis of coronary atherosclerosis. MET...
Original Research | By Marbach JA, Almufleh A, Di Santo P et al.
BACKGROUND - Incorporating focused cardiac ultrasonography (FoCUS) into clinical examination could improve the diagnostic yield of bedside patient evaluation. PURPOSE - To compare the accuracy of FoCUS-assisted clinical assessment versus clinical assessment alone for diagnosing left ventricular dysfunction or valvular disease in adults having cardiovascular evaluation. DATA SO...
Original Research | By Rissanen TT, Uskela S, DEBUT trial investigators.
BACKGROUND - The optimal technique of percutaneous coronary intervention in patients at high bleeding risk is not known. The hypothesis of the DEBUT trial was that percutaneous coronary intervention with drug-coated balloons is non-inferior to percutaneous coronary intervention with bare-metal stents for this population. METHODS - The DEBUT trial is a randomised, single-blind non-inferiority trial don...
Know Diabetes by Heart: A Partnership to Improve Cardiovascular Outcomes in Type 2 Diabetes Mellitus
Clinical Trial | By Lee MM, Petrie MC, Rocchiccioli P et al.
Original Research | By Hwang D, Kang J, Yang HM et al.
BACKGROUND - The prognostic value of angiographic complete revascularization in patients with chronic kidney disease (CKD) has not been thoroughly investigated, especially for contemporary coronary stents. We compared the clinical outcomes of complete and incomplete revascularization with second-generation drug-eluting stent, according to the presence of CKD. METHODS - From the Grand Drug-Elutin...
Original Research | By JF Iglesias, D Heg , M Roffi et al.
BACKGROUND - Randomized trials evaluating the Orsiro biodegradable polymer sirolimus-eluting stent (BP-SES; 60 and 80 μm strut thickness for stent diameters ≤3 and >3 mm, respectively) did not stratify according to vessel size and failed to specify the impact of ultrathin-strut thickness on long-term clinical outcomes compared with durable polymer everolimus-eluting stents (DP-EES). We sought to assess the long-term...
Original Research | By Schunk SJ, Zarbock A, Speer T et al.
BACKGROUND - Cardiac surgery is associated with a high risk of postoperative acute kidney injury (AKI) and subsequent loss of kidney function. We explored the clinical utility of urinary dickkopf-3 (DKK3), a renal tubular stress marker, for preoperative identification of patients at risk for AKI and subsequent kidney function loss. METHODS - This observational cohort study included patients who had cardiac s...
Review Article | By MY Desai, S Windecker, P Lancellotti et al.
Radiation-associated cardiac disease, a heterogeneous and complex disease, manifests years or even decades following radiation exposure to the chest. It is associated with a significantly higher morbidity and mortality. Often, the presentation is vague and overlaps with many diseases, presenting unique diagnostic and management issues. As a result, a high index of suspicion followed by multimodality imaging is crucial, along with comprehensiv...
Predicting Major Adverse Events in Patients With Acute Myocardial Infarction
Original Research | By T Nestelberger, J Boeddinghaus, the APACE Investigators et al.
BACKGROUND- Early and accurate detection of short-term major adverse cardiac events (MACE) in patients with suspected acute myocardial infarction (AMI) is an unmet clinical need. OBJECTIVES - The goal of this study was to test the hypothesis that adding clinical judgment and electrocardiogram findings to the European Society of Cardiology (ESC) high-sensitivity cardiac troponin (hs-cTn) me...