Review Article | By OR Ghosh-Swaby, SG Goodman, LA Leite et al.
BACKGROUND - In our 2015 systematic review and meta-analysis of cardiovascular outcome trials for glucose-lowering drugs or strategies in people with or at risk of type 2 diabetes, we reported a modest reduction in atherosclerotic cardiovascular events and an increased risk of heart failure, but with heterogeneous effects by drug or intervention type. In view of the completion of many large cardiovascular outcome trials since our previous analysi...
How Far We Have Come, How Far We Have Yet to Go in Atherosclerosis Research
Double-Kiss-Crush Bifurcation Stenting: Step-by-Step Troubleshooting
Original Research | By AB Hall, I Chavez, S Garcia et al.
The Double-Kiss-crush (DK crush) is the most studied two-stent coronary bifurcation stenting strategy. While published data support its use, DK crush can be challenging to perform. In this review we provide a detailed step-by-step description and troubleshooting for each stage of the DK crush technique.
Original Research | By R Waksman, PE Craig, R Torguson et al.
OBJECTIVES - The aim of this study was to evaluate clinical outcomes and transcatheter heart valve hemodynamic parameters after transcatheter aortic valve replacement (TAVR) in low-risk patients with bicuspid aortic stenosis (AS). BACKGROUND - TAVR is approved for low-risk patients in the United States. However, patients with bicuspid AS were excluded from the randomized cohorts o...
Original Research | By A Krishnaswamy, Y Sammour, A Mangieri et al.
OBJECTIVES - The aim of this study was to determine the utility of rapid atrial pacing immediately after transcatheter aortic valve replacement (TAVR) to predict the need for permanent pacemaker implantation (PPI). BACKGROUND - Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imprecise and based on anatomic considerations, electrocardiogra...
Clinical Trial | By Mohamed Abdel-Wahab, M Landt, Franz-Josef Neumann
OBJECTIVES -The purpose of this study was to evaluate clinical and echocardiographic outcome data of the CHOICE (Randomized Comparison of Transcatheter Heart Valves in High Risk Patients with Severe Aortic Stenosis: Medtronic CoreValve Versus Edwards SAPIEN XT) trial at 5 years. BACKGROUND - The CHOICE trial was designed to compare device performance of a balloon-expandable (BE) tran...
Frailty and Bleeding in Older Adults Undergoing TAVR or SAVR: Insights From the FRAILTY-AVR Study
Original Research | By M Bendayan, N Messas, LP Perrault et al.
OBJECTIVES - The aim of this study was to examine the value of frailty to predict in-hospital major bleeding and determine its impact on mid-term mortality following transcatheter (TAVR) or surgical (SAVR) aortic valve replacement. BACKGROUND - Bleeding complications are harbingers of mortality and major morbidity in patients undergoing TAVR or SAVR. Despite the high prevalenc...