Original Research | By MO Mohamed, J Polad, D Hildick-Smith et al.
AIMS - The present study sought to examine the prevalence, clinical characteristics and one-year outcomes of patients undergoing percutaneous coronary intervention (PCI) to complex lesions (multivessel PCI, ≥3 stents, ≥3 lesions, bifurcation with ≥2 stents, total stent length >60 mm or chronic total occlusion [CTO]) in a prospective multicentre registry. METHODS AND RESULTS - Using th...
Expert Opinion | By F Burzotta, JF Lassen, Y Louvard et al.
BACKGROUND - Defining the optimal conduction of percutaneous‐coronary‐intervention (PCI) to treat bifurcation lesions has been the subject of many clinical studies showing that the applied stenting technique may influence clinical outcome. Accordingly, bifurcation stenting classifications and technical sequences should be standardized to allow proper reporting and comparison. METHODS - The European...
Impact of Lesion Preparation Strategies on Outcomes of Left Main PCI: The EXCEL Trial
Clinical Trial | By N Beohar, S Chen, GW Stone et al.
OBJECTIVES - We examined outcomes according to lesion preparation strategy (LPS) in patients with left main coronary artery (LMCA) percutaneous coronary intervention (PCI) in the EXCEL trial. BACKGROUND - The optimal LPS for LMCA PCI is unclear. METHODS - We categorized LPS hierarchically (high to low) as: (a) rotational atherectomy (RA); (b) cut...
Review Article | By M Pepe, E Carulli, Cinzia Forleo et al.
Inflammatory bowel disease (IBD) is a pathological condition that first involves the gastrointestinal wall but can also trigger a systemic inflammatory state and thus extraintestinal manifestations. Systemic inflammation is probably secondary to the passage of bacterial products into the bloodstream because of altered intestinal permeability and the consequent release of proinflammatory mediators. Inflammation, through several dive...
Editorial | By B Asatryan, L Roten, T Reichlin et al.
The important study concerning the easy-to-use electrocardiogram (ECG) markers of sudden and/or arrhythmic death (SAD) in coronary artery disease (CAD) patients as presented by Chatterjee et al.1 is a weighty contribution to an intricate and still rather puzzling topic. They implicate that in CAD patients, contiguous Q waves, left ventricular hypertrophy (LVH), QRS duration, and JTc prolongation provide incremental predictive value...
Simple Electrocardiographic Measures Improve Sudden Arrhythmic Death Prediction in Coronary Disease
Original Research | By NA Chatterjee, JT Tikkanen, PREDETERMINE Investigators et al.
AIMS - To determine whether the combination of standard electrocardiographic (ECG) markers reflecting domains of arrhythmic risk improves sudden and/or arrhythmic death (SAD) risk stratification in patients with coronary heart disease (CHD). METHODS AND RESULTS - The association between ECG markers and SAD was examined in a derivation cohort (PREDETERMINE; N = 5462) ...
Antithrombotic Therapy in Patients With Atrial Fibrillation and Acute Coronary Syndrome
Original Research | By V Auffret, A Bakhti, G Leurent et al.
BACKGROUND - Heart failure (HF) readmission is common post-transcatheter aortic valve replacement (TAVR). Nonetheless, limited data are available regarding its predictors and clinical impact. This study evaluated the incidence, predictors, and impact of HF readmission within 1-year post-TAVR, and assessed the effects of the prescription of HF therapies at discharge on the risk of HF readmission and death. ...
Original Research | By A Czarnecki, F Qiu, KA Henning et al.
BACKGROUND - Rehospitalization rates post-transcatheter aortic valve replacement (TAVR) are high; however, it is not known how these compare with pre-TAVR hospitalization rates. Our objective was to determine the association between the index TAVR and hospitalization rates pre- and postprocedure. METHODS - A retrospective observational study was performed including all TAVR procedures perform...