Original Research | By CJ Kobylecki, BG Nordestgaard, S Afzal et al.
BACKGROUND - Circulating total calcium or albumin-adjusted calcium is a risk factor for cardiovascular disease. As the biologically active ionized calcium is a physiologically more relevant measure and its association with cardiovascular disease is poorly understood, we tested the hypothesis that high plasma ionized calcium is associated with higher risk of myocardial infarction and ischemic stroke in individuals in the g...
Original Research | By SAJ Damen, GE Cramer, H-J Dieker et al.
Unexpectedly Low Natriuretic Peptide Levels in Patients With Heart Failure
Original Research | By R von Känel, J-P Schmid, RE Meister-Langraf et al.
Original Research | By GG Schwartz, PG Steg, ODYSSEY OUTCOMES Committees and Investigators et al.
Cardiac Resynchronization Therapy and Ventricular Tachyarrhythmia Burden
Original Research | By S Tankut, I Goldenberg, V Kutyifa et al.
BACKGROUND - Cardiac resynchronization therapy-defibrillator (CRT-D) may reduce the incidence of first ventricular tachyarrhythmia (VTA) in patients with heart failure (HF) and left bundle-branch-block (LBBB). OBJECTIVE - To assess the effect of CRT-D on VTA burden in LBBB patients. METHODS - We included 1281 patients with LBBB from MADIT-CR...
When and how to use SGLT2 inhibitors in patients with HFrEF or chronic kidney disease
Original Research | By RD Kurmann, EA El-Am, YA Radwan et al.
Clinical Trial | By Z Ge, JJ Zhang, SL Chen et al.
BACKGROUND - Double kissing (DK) crush approach for patients with coronary bifurcation lesions, particularly localized at distal left main or lesions with increased complexity, is associated with significant reduction in clinical events when compared with provisional stenting (PS). Recently, randomized clinical trial has demonstrated the net clinical benefits by intravascular ultrasound (IVUS)-guided implantation of drug-eluting stent (D...