Original Research | By BJ Forrestal, BC Case, C Yerasi et al.
BACKGROUND - The supra-annular leaflet position and tall stent frame of the self-expanding Evolut PRO or Evolut PRO+ transcatheter heart valves (THVs) may cause coronary occlusion during transcatheter aortic valve replacement (TAVR)-in-TAVR and present challenges for future coronary access. We sought to evaluate the risk of TAVR-in-TAVR with Evolut PRO or Evolut PRO+ THVs and the feasibility of future cor...
Atrial Fibrillation and the Prognostic Performance of Biomarkers in Heart Failure
Original Research | By ESJ Tan, S-P Chan, O-W Liew et al.
BACKGROUND - Consideration of circulating biomarkers for risk stratification in heart failure (HF) is recommended, but the influence of atrial fibrillation (AF) on prognostic performance of many markers is unclear. We investigated the influence of AF on the prognostic performance of circulating biomarkers in HF. METHODS - N-terminal pro-B-type natriuretic peptide (NT-proBNP), mid-regional-pro-atrial natr...
Impact of bleeding during dual antiplatelet therapy in patients with coronary artery disease
Clinical Trial | By F Cosentino , CP Cannon , DZI Cherney et al.
Left main coronary artery compression in pulmonary hypertension
Original Research | By JE Labin, R Saggar, EH Yang et al.
Extrinsic compression of the left main coronary artery (LMCA) by a dilated pulmonary artery (PA) in the setting of pulmonary arterial hypertension (PAH) is an increasingly recognized disease entity. LMCA compression has been associated with angina, arrhythmia, heart failure, and sudden cardiac death in patients with PAH. Recent studies suggest that at least 6% of patients with PAH have significant LMCA compression. Screening...
Original Research | By MC Williams, D Massera, AJ Moss et al.
Clinical Case Study | By Youssef S Abdelwahed, Anne-Sophie Schatz 1 2 3 , Ulf Landmesser
A 54-year-old male complaining of recurrent chest pain on exertion (CCS 2) was electively admitted for a second recanalization attempt of a chronic totally occluded (CTO) first diagonal branch. Two years ago, a drug-eluting stent (DES) deployed to the proximal LAD jailed the diagonal ostium leading to its occlusion. Based on the angiographic analysis, seen by contrast filling through the epicardial retrograde collateral flow from the di...
Review Article | By NE Ibrahim, JL Januzzi.
BACKGROUND - Several large trials have demonstrated cardiac benefits in patients with and without established cardiovascular disease treated with sodium-glucose co-transporter 2 inhibitors (SGLT2i). Most recently, in patients with heart failure with reduced ejection fraction (HFrEF), the risk of worsening HF or cardiovascular death was lower among those who received dapagliflozin than among those who received placebo, r...