Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients
Original Research | By ML Henry, JG Niu, N Zhang et al.
OBJECTIVES - This study sought to determine the rate of chemotherapy-related cardiotoxicity and to estimate adherence to recommendations for cardiac monitoring among breast cancer patients treated with chemotherapy. BACKGROUD - Heart failure (HF) is a known complication associated with cancer therapies. Little is known regarding the rate of chemotherapy-related cardiotoxicity and adherence to recommendati...
Stress Echocardiography and PH: What Do the Findings Mean?
Expert Opinion | By Monique A. Freund, MBBS, FACC
DEFINITIONS - There are five subtypes of pulmonary hypertension (PH) in the most recent classification from the 5th World Symposium on Pulmonary Hypertension in 2013.1 Group 1 is typical pulmonary arterial hypertension (PAH), and group 2 is PH due to left heart disease. Group 2 PH is the most common subtype encountered in clinical practice, including in the stress echocardiography laboratory. Pre-capillary PH is invasively defined as...
Original Research | By Jinnouchi H, Kuramitsu S, Shinozaki T et al.
BACKGROUND - Percutaneous coronary intervention for heavily calcified lesions requires rotational atherectomy (RA). Long-term clinical outcomes after drug-eluting stent (DES) implantation following (RA) for heavily calcified lesions remain unclear. We assessed 5-year clinical outcomes after DES implantation following RA. METHODS AND RESULTS- Between March 2006 and September 2011, 219 consec...
Astro-CHARM, the First 10-year ASCVD Risk Estimator Incorporating Coronary Calcium
Expert Opinion | By Anum Minhas, MD; Roger S. Blumenthal, MD, FACC; Seth Shay Martin, MD, MHS, FACC
Approaches to cardiovascular disease risk assessment range in focus from the broad endpoint of global composite cardiovascular disease, including myocardial infarction (MI), stroke, coronary or peripheral revascularization, incident heart failure and atrial fibrillation, to more narrow approaches focused only on coronary events or cardiovascular mortality or to approaches in the middle looking at hard atherosclerotic cardiovascular disease (ASCVD) events such ...
Original Research | By A Khera , MJ Budoff , CJ O’Donnell et al.
BACKGROUND - Coronary artery calcium (CAC) is a powerful novel risk indicator for atherosclerotic cardiovascular disease (ASCVD). Currently, there is no available ASCVD risk prediction tool that integrates traditional risk factors and CAC. METHODS - To develop a CAC ASCVD risk tool for younger individuals in the general population, subjects aged 40-65 without prior CVD from three population-based...
Clinical Trial | By McClelland RL, Jorgensen NW, Budoff M et al.
BACKGROUND - Several studies have demonstrated the tremendous potential of using coronary artery calcium (CAC) in addition to traditional risk factors for coronary heart disease (CHD) risk prediction. However, to date, no risk score incorporating CAC has been developed. OBJECTIVES - The goal of this study was to derive and validate a novel risk score to estimate 10-year CHD risk using CAC and traditio...
Original Research | By JM Lee, KH Choi, D Hwang et al.
OBJECTIVES - This study investigated the prognostic implication of coronary flow reserve (CFR) in patients who underwent fractional flow reserve (FFR) measurement. BACKGROUND - Limited data are available regarding the long-term prognosis associated with thermodilution CFR in patients with coronary artery disease. METHODS - A total of 519 patients (737 vessels) who did not undergo re...