Review Article | By Boi A, Jamthikar AD, Suri JS et al.
PURPOSE OF REVIEW - Atherosclerotic plaque deposition within the coronary vessel wall leads to arterial stenosis and severe catastrophic events over time. Identification of these atherosclerotic plaque components is essential to pre-estimate the risk of cardiovascular disease (CVD) and stratify them as a high or low risk. The characterization and quantification of coronary plaque components are not only vital but also a challenging task...
Ranolazine in High-Risk Patients With Implanted Cardioverter-Defibrillators - The RAID Trial
Clinical Trial | By W Zareba, JP Daubert, CA Beck et al.
BACKGROUND - Ventricular tachycardia (VT) and ventricular fibrillation (VF) remain a challenging problem in patients with implantable cardioverter-defibrillators (ICDs). OBJECTIVES - This study aimed to determine whether ranolazine administration decreases the likelihood of VT, VF, or death in patients with an ICD. METHODS - This was double-blind, placebo-controlled clinical t...
Clinical Trial | By Kaier TE, Twerenbold R, Marber M et al.
BACKGROUND - Cardiac myosin-binding protein C (cMyC) is a cardiac-restricted protein that is more abundant than cardiac troponins (cTn) and is released more rapidly after acute myocardial infarction (AMI). We evaluated cMyC as an adjunct or alternative to cTn in the early diagnosis of AMI. METHODS - Unselected patients (N=1954) presenting to the emergency department with symptoms suggestive of AM...
Letter | By TE Kaier , R Twerenbold , C Puelacher et al.
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Letter | By XW Jiang , HW Tian and SB Qiao et al.
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Original Research | By Punthakee Z, Iglesias PP, Alonso-Coello P et al.
BACKGROUND - Myocardial injury after non-cardiac surgery (MINS) is the most common perioperative cardiovascular complication and is independently associated with 30-day mortality. We aimed to assess the association between preoperative glucose concentration and postoperative MINS and mortality. METHODS - The VISION study is a prospective cohort study done at 12 centres in eight countries. Patients aged 45 y...
Original Research | By Shavelle DM, Banerjee S, Maini B et al.
Patients with prior coronary artery bypass grafting (CABG) represent a high-risk cohort given associated medical conditions and worse outcome of saphenous vein graft compared with native vessel percutaneous coronary intervention (PCI). The goal of the current analysis was to compare clinical outcomes in 591 patients with and without prior CABG and multivessel coronary artery disease or unprotected left main disease and severely reduced lef...
Original Research | By Inaba S, Mintz GS, Yun KH et al.
AIMS - Mechanical complications contribute to bare metal and first-generation drug-eluting stent (DES) failure. However, the importance of the mechanical complications of second-generation DES remains unclear. We report mechanical complications associated with everolimus-eluting stent (EES) failures. METHODS AND RESULTS - We retrospectively analysed 177 consecutive EES-treated lesions in 136 patients w...
Clinical Trial | By Kan J, Ge Z, Chen SL et al.
OBJECTIVES - The present study aimed to analyze the incidence of SF and its correlation with clinical events after DES implantation and the outcome of re-intervention for symptomatic in-stent restenosis (ISR) induced by stent fracture (SF). BACKGROUND - SF is associated with a high rate of clinical events after the implantation of drug-eluting stents (DES). However, the chronological rate of SF and th...
Original Research | By Kang SJ, Cho YR, Park GM et al.
The aim of the present study was to assess the intravascular ultrasound predictors for angiographic edge restenosis after newer generation drug-eluting stent implantation. A total of 820 patients (987 lesions) who underwent newer generation drug-eluting stent placement (236 Endeavor zotarolimus-eluting stents, 246 Resolute zotarolimus-eluting stents, and 505 everolimus-eluting stents) with 9 months of angiographic surveillance were enrolled. The...