Clinical Trial | By H Zhang, YL Han and SL Chen et al.
BACKGROUND - Pulmonary artery denervation (PADN) has been shown to improve hemodynamics of pulmonary arterial hypertension (PAH) in a series of patients. Additionally, benefits of targeted medical therapy for patients with combined pre- and post-capillary pulmonary hypertension (CpcPH) secondary to left sided heart failure are unknown. OBJECTIVES - We sought to assess the benefits of PADN amo...
Clinical Trial | By JJ Zhang, XF Gao, SL Chen et al.
BACKGROUND - Intravascular ultrasound (IVUS)-guided drug-eluting stent (DES) implantation is associated with less major adverse cardiovascular events (MACE) compared with angiography guidance for patients with individual lesion subset. However, the beneficiary effect on MACE outcome of IVUS guidance over angiography guidance in all-comers who undergo DES implantation still remains understudied. ...
Original Research | By Madder RD, VanOosterhout SM, Jacoby ME et al.
AIMS - The present study explores the feasibility of telestenting, wherein a physician operator performs stenting on a patient in a separate physical location using a combination of robotics and telecommunications. METHODS AND RESULTS - Patients undergoing robotic stenting were eligible for inclusion. All manipulations of guidewires, balloons, and stents were performed robotically by a physician operator ...
Original Research | By Mintz GS1, Popma JJ, Pichard AD et al.
BACKGROUND - Target lesion calcium is a marker for significant coronary artery disease and a determinant of the success of transcatheter therapy. METHODS AND RESULTS - Eleven hundred fifty-five native vessel target lesions in 1117 patients were studied by intravascular ultrasound (IVUS) and coronary angiography. The presence, magnitude, location, and distribution of IVUS calcium were analyzed an...
Coronary artery imaging with intravascular high-frequency ultrasound
Original Research | By Potkin BN, Bartorelli AL, Gessert JM et al.
Safe and effective clinical application of new interventional therapies may require more precise imaging of atherosclerotic coronary arteries. To determine the reliability of catheter-based intravascular ultrasound as an imaging modality, a miniaturized prototype ultrasound system (1-mm transducer; center frequency, 25 MHz) was used to acquire two-dimensional, cross-sectional images in 21 human coronary arteries from 13 patients studied at nec...
Original Research | By Lee JB, Mintz GS, Lisauskas JB et al.
A calcified nodule is a type of potentially vulnerable plaque accounting for approximately 2% to 7% of coronary events. Because its intravascular ultrasound (IVUS) features have never been validated, the aim of this study was to assess the IVUS characteristics of calcified nodules in comparison to histopathology. IVUS was performed in 856 pathologic slices in 29 coronary arteries (11 left anterior descending, 5 left circumflex, and 13 right cor...