Medical Therapy for CTEPH: Is There Still Space for More?
Expert Opinion | By Roela Sadushi-Kolici, MD; Irene Marthe Lang, MD
Background - Venous thromboembolism, clinically presenting as deep vein thrombosis or pulmonary embolism (PE), is globally the third most frequent acute cardiovascular syndrome behind myocardial infarction and stroke. Annual incidence for acute PE ranges from 39 to 115 per 100,000. Abnormal persistence thrombi as fibrous residua combined with a variable microscopic pulmonary vasculopathy may lead to chronic thromboembolic pulmonary ...
Update on chronic thromboembolic pulmonary hypertension
Original Research | By Mizoguchi H, Ogawa A, Munemasa M et al.
Original Research | By Dorfmüller P, Günther S, Ghigna MR et al.
Original Research | By Moser KM, Bloor CM.
The status of small pulmonary arteries may influence diagnosis, surgical selection and postoperative outcome of patients with chronic major vessel thromboembolic pulmonary hypertension (CTEPH). Therefore, in patients with the established diagnosis of CTEPH, lung tissue was obtained by biopsy (15 patients) or at autopsy (16 patients) to assess the histopathologic composition of small pulmonary arteries. Pathologic examination disc...
Advances in therapeutic interventions for patients with pulmonary arterial hypertension
Chronic thromboembolic pulmonary hypertension
Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review
Review Article | By M.G.D Buono, R Arena, BA Borlaug et al.
Exercise intolerance is the cardinal symptom of heart failure (HF) and is of crucial relevance, because it is associated with a poor quality of life and increased mortality. While impaired cardiac reserve is considered to be central in HF, reduced exercise and functional capacity are the result of key patient characteristics and multisystem dysfunction, including aging, impaired pulmonary reserve, as well as peripheral and respir...
Review Article | By JC Jentzer, J Herrmann, A Prasad et al.
Out-of-hospital cardiac arrest (OHCA) is frequently triggered by acute myocardial ischemia. Coronary angiography is an important component of post-resuscitation care for patients with OHCA without an evident noncardiac cause, to identify underlying coronary artery disease and allow revascularization. Most patients undergoing coronary angiography after OHCA have obstructive coronary artery disease, and nearly one-half of patients have acute coronary oc...
Original Research | By JS Shavadia, AY Chen, AC Fanaroff et al.
OBJECTIVES - The aims of this study were to describe variability in intensive care unit (ICU) utilization for patients with uncomplicated ST-segment elevation myocardial infarction (STEMI), evaluate the proportion of these patients who developed in-hospital complications requiring ICU care, and assess whether ICU use patterns and complication rates vary across categories of first medical contact to device times. ...