Prognostic value of coronary artery calcium screening in subjects with and without diabetes
Guideline | By Greenland P, American College of Cardiology Foundation; American Heart Association.
Original Research | By JM Lee, KH Choi, B-K Koo et al.
BACKGROUND- Although the presence of ischemia is a key prognostic factor in patients with coronary artery disease, the presence of high-risk plaque characteristics (HRPC) is also associated with increased risk of cardiovascular events. Limited data exist regarding the prognostic implications of combined information on physiological stenosis severity assessed by fractional flow reserve (FFR) and plaque vulnerability by coronary computed...
Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction
Original Research | By SJ Greene, GC Fonarow, AD DeVore et al.
BACKGROUND - Guidelines recommend that patients with heart failure with reduced ejection fraction (HFrEF) have medical therapy titrated to target doses derived from clinical trials, as tolerated. The degree to which titration occurs in contemporary U.S. practice is unknown. OBJECTIVES - This study sought to characterize longitudinal titration of HFrEF medical therapy in clinical practice and to identi...
Recommandation Statement | By E Spitzer, E McFadden, PW Serruys et al.
The Academic Research Consortium (ARC) and the Standardized Data Collection for Cardiovascular Trials Initiative have recently published updated clinical and angiographic endpoint definitions for percutaneous coronary intervention trials. The aim of this document is to provide practical guidance to facilitate and harmonize the implementation of those definitions in randomized trials or registries, as well as to foster consi...
EXCELling in Left Main Intervention
Review Article | By Kirtane AJ, Bonow RO.
It can be argued that severe left main coronary artery (LMCA) disease represents the only anatomic subtype of coronary artery disease for which there is clear and unequivocal prognostic evidence in favor of coronary revascularization across the spectrum of clinical presentation—from stable ischemic heart disease to acute coronary syndrome. For decades, the standard approach to LMCA revascularization has been through coronary artery bypass graft...
Original Research | By Zlotnick DM, Ramanath VS, Brown JR et al.
BACKGROUND - Coronary bifurcation lesions are common, difficult to treat, and associated with poorer outcomes compared to non-bifurcation lesions. The Medina classification has been widely adopted as the preferred system to classify bifurcation lesions, however there have been little efforts to characterize this metric. The objective of this study was to characterize the inter-observer variability of the Medina classification and exa...