Galectin-3 Levels and Outcomes After Myocardial Infarction: A Population-Based Study
Original Research | By Asleh R, Enriquez-Sarano M, Jaffe AS et al.
BACKGROUND - Galectin-3 (Gal-3) is implicated in cardiac fibrosis, but its association with adverse outcomes after myocardial infarction (MI) is unknown. OBJECTIVES - The purpose of this study was to examine the prognostic value of Gal-3 in a community cohort of incident MI. METHODS - A population-based incidence MI cohort was prospectively assembled in Olmsted County, Minne...
IMPORTANCE - Physicians have been criticized for having an overly enthusiastic response to new device approvals, especially for novel technologies. However, to our knowledge, the rates of new product adoption and patterns of new device usage in clinical practice have not been well described. OBJECTIVE - To characterize the patterns of uptake of bioresorbable vascular scaffolds (BVS) within the United States follow...
Can the Vanishing Stent Reappear? Fix the Technique, or Fix the Device?
Original Research | By A Ghimire, N Fine, FA McAlister et al.
AIMS - To identify variables predicting ejection fraction (EF) recovery and characterize prognosis of heart failure (HF) patients with EF recovery (HFrecEF). METHODS AND RESULTS - RETROSPECTIVE study of adults referred for ≥2 echocardiograms separated by ≥6 months between 2008 and 2016 at the two largest echocardiography centres in Alberta who also had physician-assigned diagnosis of HF...
Guideline | By Al-Khatib SM, Stevenson WG, Ackerman MJ et al.
Healed Culprit Plaques in Patients With Acute Coronary Syndromes
Original Research | By Fracassi F, Crea F, Jang IK et al.
BACKGROUND - Healed plaques, morphologically characterized by a layered phenotype, are frequently found in subjects with sudden cardiac death. However, in vivo data are lacking. OBJECTIVES- The purpose of this study was to determine the prevalence, morphological characteristics, and clinical significance of healed culprit plaques in patients with acute coronary syndromes (ACS) using optical coherenc...
Original Research | By P Guedeney, BE Claessen, DN Kalkman et al.
BACKGROUND - Data on the impact of residual inflammatory risk (RIR) in patients undergoing percutaneous coronary intervention (PCI) with baseline low-density lipoprotein cholesterol (LDL-C) ≤70 mg/dl are scarce. OBJECTIVES - The purpose of this study was to characterize the prevalence and impact of persistent high RIR after PCI in patients with baseline LDL-C ≤70 mg/dl. METHOD...
Coronary calcification in the diagnosis of coronary artery disease
Review Article | By Rifkin RD, Parisi AF, Folland E.
Clinical, postmortem and angiographic studies of coronary calcification are reviewed to define the value of fluoroscopy in the diagnosis and management of coronary artery disease. Autopsy studies consistently show a unique association between calcification of the coronary arteries and atherosclerosis. The relation of coronary calcification to the presence of major stenosis is more variable but is strong enough to be of clinical value, particularly in the youn...
Coronary calcium as a predictor of coronary events in four racial or ethnic groups
Original Research | By Detrano R, Guerci AD, Carr JJ et al.
BACKGROUND - In white populations, computed tomographic measurements of coronary-artery calcium predict coronary heart disease independently of traditional coronary risk factors. However, it is not known whether coronary-artery calcium predicts coronary heart disease in other racial or ethnic groups. METHODS - We collected data on risk factors and performed scanning for coronary calcium in a population-base...