Original Research | By DGD Rocca, M Magnocavallo, LD Biase et al.
OBJECTIVES - This study evaluated the long-term efficacy of a standard antithrombotic strategy versus half-dose direct oral anticoagulation (DOAC) after Watchman implantation. BACKGROUND - No consensus currently exists on the selection of the most effective antithrombotic strategy to prevent device-related thrombosis (DRT) in patients undergoing endocardial left atrial appendage closure. ...
Clinical Trial | By JB Cohen, SJ Schrauben, JA Chirinos et al.
Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
Clinical Trial | By VJ Nijenhuis, J Brouwer, R Delewi et al.
Edoxaban versus Vitamin K Antagonist for Atrial Fibrillation after TAVR
Clinical Trial | By NM Van Mieghem, M Unverdorben, the ENVISAGE-TAVI AF Investigators.
BACKGROUND - The role of direct oral anticoagulants as compared with vitamin K antagonists for atrial fibrillation after successful transcatheter aortic-valve replacement (TAVR) has not been well studied. METHODS - We conducted a multicenter, prospective, randomized, open-label, adjudicator-masked trial comparing edoxaban with vitamin K antagonists in patients with prevalent or incident atrial fibrillation as the indic...
Clinical Trial | By J Butler, G Filippatos, TJ Siddiqi et al.
Global Chronic Total Occlusion Crossing Algorithm: JACC State-of-the-Art Review
Review Article | By EB Wu , ES Brilakis, K Mashayekhi et al.
Original Research | By BH Strauss, ML Knudtson, AN Cheema et al.
BACKGROUND - Chronic total occlusions (CTO) occur in nearly 20% of coronary angiograms. CTO revascularization, either by percutaneous coronary intervention (PCI) or coronary artery bypass grafting surgery (CABG), is infrequently performed, approximately one-third of cases. Long-term outcomes are unknown. The objective of the study was to determine whether early CTO revascularization of patients, either by CABG or PCI, was associ...
Consensus | By J Herrmann, D Lenihan, S Armenian et al.
The discipline of Cardio-Oncology has seen tremendous growth over the past decade. It is devoted to the cardiovascular (CV) care of the cancer patient, especially to the mitigation and management of CV complications or toxicities of cancer therapies, which can have profound implications on prognosis. To that effect, many studies have assessed CV toxicities in patients undergoing various types of cancer therapies; however, direct comparisons...
Original Research | By A Banerjee, L Pasea, S-C Chung et al.
BACKGROUND - Primary prevention strategies for heart failure(HF) have had limited success, possibly due to a wide range of underlying risk factors(RFs). Systematic evaluations of the prognostic burden and preventive potential across this wide range of risk factors are lacking. OBJECTIVE - To estimate evidence, prevalence and co-occurrence for primary prevention and impact on prognosis of RFs for incident HF. &...