Future of Personalized Cardiovascular Medicine
Previous decades have seen significant progress in the biological understanding of cardiovascular disease, as well as major advances in computational and information technologies. However, anticipated improvements in outcomes, quality, and cost of cardiovascular medicine at the individual and population levels from these advances have lagged expectations. Further, trends showing widening gaps in the pace of technological developm...
Clinician’s Guide to Reducing Inflammation to Reduce Atherothrombotic Risk
Life-threatening cardiovascular events occur despite control of conventional risk factors. Inflammation, as measured by high-sensitivity C-reactive protein (hsCRP) concentration, is associated with future vascular events in both primary and secondary prevention, independent of usual risk markers. Statins are powerful lipid-lowering agents with clinically relevant anti-inflammatory effects. Recent data support targeting the inte...
Disrupting Fellow Education Through Group Texting: WhatsApp in Fellow Education?
Perspective | By A Kochar, J Rymer, Duke Cardiovascular Education Group et al.
Covering our tracks – optical coherence tomography to assess vascular healing
Editorial | By ZA Ali, KK Galougahi, AV Finn.
Over the better part of two decades, lessons learned from stent failure have led to technical advances that have resulted in current-generation metallic drug-eluting stents (DES) with very low rates of target lesion failure (TLF) and stent thrombosis1. Continued efforts have been directed at achieving iterative improvements in the design of DES to enhance adaptive vascular healing following vascular injury. By promoting ear...
Original Research | By Tamaru H, Fujii K, Nakata T et al.
This study evaluated the impact of optical coherence tomography (OCT)-derived low-backscattered tissue on mid-term coronary endothelial function after drug-eluting stent (DES) implantation. Although OCT enables detailed in vivo evaluation of neointimal tissue characterization after DES implantation, its association with physiological vascula rhealing response is unclear. Thirty-three stable angina pectoris patients underw...
Histopathological validation of optical coherence tomography findings of the coronary arteries
Review Article | By Fujii K, Kawakami R, Hirota S.
Optical coherence tomography (OCT), a catheter-based imaging modality for the visualization of coronary arteries, is widely used during percutaneous coronary intervention to improve the understanding of the anatomy of coronary artery stenosis and to elucidate the mechanisms of atherosclerosis. In this review, we provide a short description of the histopathological validations of OCT for visualizing atherosclerotic plaques and vasc...
Drug-Drug Interactions of Common Cardiac Medications and Chemotherapeutic Agents
Expert Opinion | By S Zukkoor, V Thohan.
As the field of cardio-oncology evolves, the focus of treatment has shifted from reactive to proactive care. Prevention of cancer therapy-related cardiac dysfunction through optimization of cardiac risk factors and periodic surveillance, as well as minimal interruption of cancer treatment, is the emphasis of modern treatment paradigms.1 Cardio-protection frequently involves the initiation of cardiac medications, including certain beta-bloc...
Expert Opinion | By Lancellotti P, Suter TM, López-Fernández T et al.
Prevalence of potential drug-drug interactions in cancer patients treated with oral anticancer drugs
Original Research | By van Leeuwen RW, Brundel DH, Neef C et al.
Original Research | By Watanabe M, Okura H, Okamura A et al.
OBJECTIVES - The aim is to investigate the usefulness of longitudinal reconstructed optical coherence tomography (OCT) images in selecting the reverse wire (RW) technique for inserting a guidewire into a side branch (SB). BACKGROUND - It is sometimes necessary to protect the SB with a guidewire to prevent SB complications in PCI for bifurcation lesions. The RW is a novel method for guidewir...