Original Research | By AB Ingason, JP Hreinsson, ES Björnsson et al.
BACKGROUND - Gastrointestinal bleeding (GIB) rates for direct oral anticoagulants (DOACs) and warfarin have been extensively compared. However, population-based studies comparing GIB rates among different DOACs are limited. OBJECTIVE - To compare rates of GIB among apixaban, dabigatran, and rivaroxaban. DESIGN - Nationwide population-based cohort study. SETTING - Lan...
Original Research | By A Czarnecki , L Han , W Abuzeid et al.
OBJECTIVES - The objective of this study was to determine the effect of transcatheter mitral valve repair (TMVr) on hospitalization rates by assessing pre- and postprocedural hospitalization patterns. BACKGROUND - TMVr has emerged as the treatment of choice for selected patients with mitral regurgitation, but the impact of these procedures on hospital utilization remains unclear. METH...
Guideline | By Writing Committee Members, M Gulati , PD Levy et al.
Original Research | By VC Babaliaros, RJ Lederman, PT Gleason et al.
The SAPIEN 3 is the only transcatheter heart valve commercially available for compassionate transcatheter mitral valve replacement in patients with previous mitral surgical rings and mitral annular calcification (valve in ring [VIR] and valve in mitral annular calcification [VIM]). Reported outcomes have been inconsistent or poor. The review provides an overview of the authors’ approach to achieve largely consistent results despite the ...
Original Research | By D Tomii, T Okuno, F Praz et al.
OBJECTIVES - The aims of this study were to document the prevalence of concomitant tricuspid regurgitation (TR) before and after transcatheter aortic valve replacement (TAVR), to quantify potential eligibility for transcatheter tricuspid valve intervention (TTVI), and to report clinical outcomes as a function of the severity of TR and potential candidacy for TTVI. BACKGROUND - The importance of concomitant TR in ...
Lateral Wall Dysfunction Signals Onset of Progressive Heart Failure in Left Bundle Branch Block
Evolution of the Crush Technique for Bifurcation Stenting
Review Article | By S Chatterjee, AC Fanaroff, C Parzynski et al.
Bifurcation lesions are frequently encountered, associated with greater procedural complexity and consequently are at higher risk for restenosis and stent thrombosis. Early trials in bifurcation percutaneous coronary intervention favored a provisional stenting approach, but contemporary randomized trials have highlighted potentially superior outcomes using a double-kiss crush technique in unprotected distal left main stem bifurcation lesions. Althoug...
Treating Bifurcation Lesions: The Result Overcomes the Technique
Haemodynamic-guided management of heart failure (GUIDE-HF): a randomised controlled trial
Clinical Trial | By JA Lindenfeld, MR Zile, AS Desai et al.
BACKGROUND - Previous studies have suggested that haemodynamic-guided management using an implantable pulmonary artery pressure monitor reduces heart failure hospitalisations in patients with moderately symptomatic (New York Heart Association [NYHA] functional class III) chronic heart failure and a hospitalisation in the past year, irrespective of ejection fraction. It is unclear if these benefits extend to patients with mild (...